Medication-Assisted Treatment for Opioid Addiction: A Guide

MAT uses FDA-approved medications (methadone, buprenorphine, naltrexone) with counseling. MAT patients have 59% lower overdose death risk, cut all-cause death risk in half. Without MAT, 59% relapse within one week after detox.
- 1Fewer than 1 in 5 people with opioid use disorder receive MAT
- 2Three FDA-approved medications: Methadone, Buprenorphine, Naltrexone
- 3MAT patients had 59% lower risk of dying from opioid overdose
- 459% relapsed within one week after detox without MAT
- 5Patients on MAT 15+ months showed significantly lower relapse rates
Medication-Assisted Treatment for Opioid Addiction: A Guide
Medication-assisted treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies. Despite its effectiveness, MAT remains underutilized for opioid addiction treatment.
Understanding MAT
What Is MAT?
Medication-assisted treatment involves:
- FDA-approved medications
- Combined with counseling
- Behavioral therapies
- Whole-patient approach
- Evidence-based effectiveness
Why MAT Matters
The treatment gap is significant:
- Fewer than 1 in 5 people with opioid use disorder receive MAT
- Highly effective when available
- Reduces mortality significantly
- Improves treatment outcomes
- Decreases criminal activity
How Effective is MAT?
Mortality Reduction
MAT saves lives:
- Patients had 59% lower risk of dying from opioid overdose
- MAT recipients cut risk of death from all causes in half
- Prevents fatal overdoses
- Stabilizes brain chemistry
- Allows focus on recovery
Relapse Prevention
Without MAT, outcomes are poor:
- 59% relapsed within one week after detox alone
- MAT dramatically improves retention
- Patients on MAT 15+ months showed significantly lower relapse rates
- Long-term treatment produces best outcomes
Additional Benefits
MAT also:
- Decreases opioid use
- Reduces criminal activity
- Improves employment
- Enhances social functioning
- Decreases infectious disease transmission
FDA-Approved Medications
Methadone
How it works:
- Full opioid agonist
- Prevents withdrawal and cravings
- Long-acting (24+ hours)
- Dispensed daily at clinics
- Highly effective for severe addiction
Buprenorphine (Suboxone)
Characteristics:
- Partial opioid agonist
- Lower overdose risk
- Can be prescribed by qualified physicians
- Taken at home (after stabilization)
- Combined with naloxone to deter misuse
Naltrexone (Vivitrol)
How it works:
- Opioid antagonist (blocks effects)
- No abuse potential
- Monthly injection available
- Requires complete detox first
- Good for motivated individuals
Dispelling MAT Myths
Myth: "MAT Is Just Substituting One Drug for Another"
Reality:
- MAT medications are FDA-approved treatments
- They normalize brain chemistry
- Taken as prescribed, they don't produce euphoria
- Similar to treating diabetes with insulin
- Part of comprehensive treatment
Myth: "You're Not Really Sober on MAT"
Reality:
- MAT stabilizes brain function
- Allows normal daily functioning
- Removes obsessive drug-seeking
- Supports recovery activities
- Many recover successfully with MAT
Myth: "MAT Should Only Be Short-Term"
Reality:
- Duration should be individualized
- Some need long-term or indefinite treatment
- Stopping too soon increases relapse risk
- 15+ months shows best outcomes
- Treatment decisions made with patient
Myth: "MAT Isn't Real Treatment"
Reality:
- MAT is evidence-based medicine
- Supported by decades of research
- Endorsed by major medical organizations
- Most effective treatment available
- Combines medication with therapy
Getting Started with MAT
Finding Treatment
Access options:
- SAMHSA treatment locator
- Primary care physicians (buprenorphine)
- Opioid treatment programs (methadone)
- Addiction specialists
- Hospital-based programs
What to Expect
Treatment process:
- Comprehensive assessment
- Medication selection based on needs
- Counseling and behavioral therapy
- Regular monitoring
- Ongoing support
Final Thoughts
Medication-assisted treatment represents the most effective approach for opioid addiction, significantly reducing overdose deaths and improving outcomes. Despite persistent myths, MAT is evidence-based medicine that saves lives.
Amity Behavioral Health offers MAT as part of comprehensive opioid addiction treatment. Contact us to learn about your options.
Amity BH Clinical Team
Amity BH Clinical Team is part of the clinical team at Amity Behavioral Health, dedicated to providing evidence-based treatment and compassionate care for individuals struggling with addiction and mental health challenges.
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